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1.
Radiographics ; 44(3): e230143, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38421913

RESUMEN

Cone-beam CT (CBCT) is a promising tool with increasing applications in musculoskeletal imaging due to its ability to provide thin-section CT images of the appendicular skeleton and introduce weight bearing, which accounts for loading forces that typically interact with and affect this anatomy. CBCT devices include an x-ray source directly opposite a digital silicon detector panel that performs a single rotation around an object of interest, obtaining thin-section images. Currently, the majority of research has been focused on the utility of CBCT with foot and ankle pathologic abnormalities, due to the complex architectural arrangement of the tarsal bones and weight-bearing nature of the lower extremities. Associated software can provide a variety of options for image reconstruction, including metal artifact reduction, three-dimensional biometric measurements, and digitally reconstructed radiographs. Advancements in this technology have allowed imaging of the knee, hip, hand, and elbow. As more data are published, it is becoming evident that CBCT provides many additional benefits, including fast imaging time, low radiation dose, lower cost, and small equipment footprint. These benefits allow placement of CBCT units outside of the traditional radiology department, including the orthopedic clinic setting. These technologic developments have motivated clinicians to define the scope of CBCT for diagnostics, surgical planning, and longitudinal imaging. As efforts are made to create standardized protocol and measurements, the current understanding and surgical approach for various orthopedic pathologic conditions will continue to shift, with the hope of improving outcomes. ©RSNA, 2024 Test Your Knowledge questions for this article are available in the supplemental material.


Asunto(s)
Tomografía Computarizada de Haz Cónico , Programas Informáticos , Humanos , Tomografía Computarizada de Haz Cónico/métodos , Mano , Extremidad Inferior
2.
Neuroscience ; 542: 59-68, 2024 Mar 26.
Artículo en Inglés | MEDLINE | ID: mdl-38369007

RESUMEN

Brain Computer Interface (BCI) is a highly promising human-computer interaction method that can utilize brain signals to control external devices. BCI based on functional near-infrared spectroscopy (fNIRS) is considered a relatively new and promising paradigm. fNIRS is a technique of measuring functional changes in cerebral hemodynamics. It detects changes in the hemodynamic activity of the cerebral cortex by measuring oxyhemoglobin and deoxyhemoglobin (HbR) concentrations and inversely predicts the neural activity of the brain. At the present time, Deep learning (DL) methods have not been widely used in fNIRS decoding, and there are fewer studies considering both spatial and temporal dimensions for fNIRS classification. To solve these problems, we proposed an end-to-end hybrid neural network for feature extraction of fNIRS. The method utilizes a spatial-temporal convolutional layer for automatic extraction of temporally valid information and uses a spatial attention mechanism to extract spatially localized information. A temporal convolutional network (TCN) is used to further utilize the temporal information of fNIRS before the fully connected layer. We validated our approach on a publicly available dataset including 29 subjects, including left-hand and right-hand motor imagery (MI), mental arithmetic (MA), and a baseline task. The results show that the method has few training parameters and high accuracy, providing a meaningful reference for BCI development.


Asunto(s)
Interfaces Cerebro-Computador , Espectroscopía Infrarroja Corta , Humanos , Espectroscopía Infrarroja Corta/métodos , Redes Neurales de la Computación , Algoritmos , Corteza Cerebral/diagnóstico por imagen , Mano , Electroencefalografía/métodos , Imaginación
3.
Zhongguo Zhen Jiu ; 44(2): 149-152, 2024 Feb 12.
Artículo en Inglés, Chino | MEDLINE | ID: mdl-38373759

RESUMEN

OBJECTIVES: To compare the clinical effect of fast needling (without needle retaining), needle retaining acupuncture combined with occupational therapy and simple occupational therapy for hand dysfunction of spastic cerebral palsy in children. METHODS: A total of 75 children with spastic cerebral palsy were randomly divided into an occupational therapy group (25 cases), a fast needling group (25 cases, 1 case dropped out) and a needle retaining group (25 cases, 1 case dropped out). The patients in the occupational therapy group were only treated with occupational therapy for 20 min each time. The patients in the fast needling group were treated with acupuncture (without needle retaining) combined with occupational therapy, and the needle retaining group was treated with acupuncture (needle retaining) combined with occupational therapy, and acupuncture was taken at Hegu (LI 4), Houxi (SI 3), Yuji (LU 10), Waiguan (SJ 5), Jianyu (LI 15) and so on. The needles were retained for 30 min in patients of the needle retaining group. All the above treatments were performed once a day, 5 times a week for 12 weeks. The scores of fine motor function measure (FMFM) and Peabody developmental motor scale 2 (PDMS-2) were observed in patients of the three groups before and after treatment, and the safety of the fast needling group and the needle retaining group was compared. RESULTS: After treatment, the scores of FMFM and PDMS-2 in patients of the three groups were higher than those before treatment (P<0.01), and the scores of FMFM and PDMS-2 in the fast needling group and the needle retaining group were higher than those in the occupational therapy group (P<0.05, P<0.01). The incidence of acupuncture abnormalities in the fast needling group was 0.3% (5/1 440), which was lower than 1.4% (20/1 440) in the needle retaining group (P<0.05). CONCLUSIONS: Acupuncture combined with occupational therapy has better clinical effect than occupational therapy alone in improving hand dysfunction in children with spastic cerebral palsy, and there is no statistical difference in effect between fast needling acupuncture and needle retaining acupuncture, but fast needling has better safety than needle retaining acupuncture.


Asunto(s)
Terapia por Acupuntura , Parálisis Cerebral , Terapia Ocupacional , Niño , Humanos , Parálisis Cerebral/terapia , Inducción Percutánea del Colágeno , Extremidad Superior , Mano , Resultado del Tratamiento , Puntos de Acupuntura
4.
Neuroimage Clin ; 41: 103568, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38277807

RESUMEN

INTRODUCTION: Neonatal arterial ischemic stroke (NAIS) is a common model to study the impact of a unilateral early brain insult on developmental brain plasticity and the appearance of long-term outcomes. Motor difficulties that may arise are typically related to poor function of the affected (contra-lesioned) hand, but surprisingly also of the ipsilesional hand. Although many longitudinal studies after NAIS have shown that predicting the occurrence of gross motor difficulties is easier, accurately predicting hand motor function (for both hands) from morphometric MRI remains complicated. The hypothesis of an association between the structural organization of the basal ganglia (BG) and thalamus with hand motor function seems intuitive given their key role in sensorimotor function. Neuroimaging studies have frequently investigated these structures to evaluate the correlation between their volumes and motor function following early brain injury. However, the results have been controversial. We hypothesize the involvement of other structural parameters. METHOD: The study involves 35 children (mean age 7.3 years, SD 0.4) with middle cerebral artery NAIS who underwent a structural T1-weighted 3D MRI and clinical examination to assess manual dexterity using the Box and Blocks Test (BBT). Graphs are used to represent high-level structural information of the BG and thalami (volumes, elongations, distances) measured from the MRI. A graph neural network (GNN) is proposed to predict children's hand motor function through a graph regression. To reduce the impact of external factors on motor function (such as behavior and cognition), we calculate a BBT score ratio for each child and hand. RESULTS: The results indicate a significant correlation between the score ratios predicted by our method and the actual score ratios of both hands (p < 0.05), together with a relatively high accuracy of prediction (mean L1 distance < 0.03). The structural information seems to have a different influence on each hand's motor function. The affected hand's motor function is more correlated with the volume, while the 'unaffected' hand function is more correlated with the elongation of the structures. Experiments emphasize the importance of considering the whole macrostructural organization of the basal ganglia and thalami networks, rather than the volume alone, to predict hand motor function. CONCLUSION: There is a significant correlation between the structural characteristics of the basal ganglia/thalami and motor function in both hands. These results support the use of MRI macrostructural features of the basal ganglia and thalamus as an early biomarker for predicting motor function in both hands after early brain injury.


Asunto(s)
Lesiones Encefálicas , Accidente Cerebrovascular Isquémico , Accidente Cerebrovascular , Niño , Recién Nacido , Humanos , Encéfalo , Imagen por Resonancia Magnética/métodos , Mano , Ganglios Basales/diagnóstico por imagen , Lesiones Encefálicas/complicaciones , Tálamo/diagnóstico por imagen
5.
J Neural Eng ; 21(1)2024 01 17.
Artículo en Inglés | MEDLINE | ID: mdl-38167234

RESUMEN

Objective: Current efforts to build reliable brain-computer interfaces (BCI) span multiple axes from hardware, to software, to more sophisticated experimental protocols, and personalized approaches. However, despite these abundant efforts, there is still room for significant improvement. We argue that a rather overlooked direction lies in linking BCI protocols with recent advances in fundamental neuroscience.Approach: In light of these advances, and particularly the characterization of the burst-like nature of beta frequency band activity and the diversity of beta bursts, we revisit the role of beta activity in 'left vs. right hand' motor imagery (MI) tasks. Current decoding approaches for such tasks take advantage of the fact that MI generates time-locked changes in induced power in the sensorimotor cortex and rely on band-passed power changes in single or multiple channels. Although little is known about the dynamics of beta burst activity during MI, we hypothesized that beta bursts should be modulated in a way analogous to their activity during performance of real upper limb movements.Main results and Significance: We show that classification features based on patterns of beta burst modulations yield decoding results that are equivalent to or better than typically used beta power across multiple open electroencephalography datasets, thus providing insights into the specificity of these bio-markers.


Asunto(s)
Interfaces Cerebro-Computador , Electroencefalografía/métodos , Imágenes en Psicoterapia , Movimiento , Mano , Imaginación , Algoritmos
6.
Curr Rheumatol Rev ; 20(1): 39-45, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-37691222

RESUMEN

OBJECTIVE: Osteoarthritis (OA) is one of the most prevalent joint disorders in the world that has placed an enormous economic and social burden on governments and healthcare sectors in many countries. Hand OA (HOA) is the most common peripheral arthritis, which is less investigated than knee and hip OA. Due to limited approved drug choices and adverse effects of long-term use of current regimens, we aimed to review the existing evidence that were used as oral herbal medicine to treat HOA. METHODS: The PubMed database was searched for both observational and interventional studies that have investigated herbal medicine safety and efficacy in HOA, written in English and published between 2010 and 2022. RESULTS: A total of 5 original articles fulfilled the inclusion criteria, and each article assessed a different herbal regimen. Overall, it seems desirable to add specific herbal treatments to the regimen of HOA patients, specifically in case of early stages of HOA. CONCLUSION: Currently, the need for a low-risk alternative treatment in HOA patients is felt more than ever. There are reliable references relating to the safety of Korean red ginseng, GCSB-5, XLGB, and GS-GCu in these patients, although their efficacy was limited. Additionally, herbs like curcumin and Boswellia serrata have positively affected patients with knee osteoarthritis. However, there is a lack of strong evidence supporting their effectiveness in hand osteoarthritis (HOA). This emphasizes the potential benefits that these herbs may have for HOA patients.


Asunto(s)
Curcumina , Osteoartritis de la Cadera , Osteoartritis de la Rodilla , Humanos , Osteoartritis de la Rodilla/tratamiento farmacológico , Extractos Vegetales/uso terapéutico , Osteoartritis de la Cadera/tratamiento farmacológico , Curcumina/uso terapéutico , Mano
7.
Artículo en Inglés | MEDLINE | ID: mdl-38083543

RESUMEN

Mirror visual feedback (MVF) intervention is an adjunctive approach for motor recovery after stroke. It has been hypothesized that MVF can increase visual perception, motor imagery, and attention of/to the hands. However, neuroimaging evidence for this hypothesis is still lacking. In this study, we used a hand mental rotation task and event-related potential (ERP) analysis to explore the effect of MVF intervention on visual perception, motor preparation, and motor imagery of hands. We recruited 46 patients and randomly divided them into a mirror visual feedback group (MG) and a conventional intervention group (CG). By comparing ERP amplitude between the two groups and between before and after the intervention, we found that the N200 component, which was considered to be related to motor preparation, was significantly less negative in the affected hemisphere than that in the unaffected counterpart. After intervention, the N200 amplitude became more negative, reflecting a recovery of motor preparation. Specifically, MG showed a significant effect on the N200 for the hand pictures at large orientations, while the CG showed an effect mainly for the upright hand stimuli. The results suggested an improvement of preparation for motor imagery of complex and precise hand movements after MVF intervention.Clinical Relevance- This study might be helpful for understanding the neural mechanisms of MVF which can help stroke patients regain upper extremity function.


Asunto(s)
Retroalimentación Sensorial , Accidente Cerebrovascular , Humanos , Potenciales Evocados , Mano , Accidente Cerebrovascular/terapia , Extremidad Superior
8.
Acta Cir Bras ; 38: e384323, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37909593

RESUMEN

PURPOSE: The primary objective of this study was to compare the WALANT (wide awake, local anesthesia, no tourniquet) technique with local anesthesia associated with sedation in relation to pain intensity for minor hand surgical procedures. The secondary objective was to evaluate the need for analgesic complementation. METHODS: A prospective, randomized, comparative, and clinical study was carried out. The sample size in each group was determined after statistical evaluation of the results of a pilot project. The participants were allocated to one of two groups; those in group 1 were submitted to the WALANT technique, and those in group 2, to local anesthesia associated with sedation, for elective surgery. The surgical procedures were carpal tunnel syndrome, De Quervain's tenosynovitis, synovial cyst, finger cyst, and trigger finger. Pain intensity, need for complementation and evolution to complex regional pain syndrome were evaluated. RESULTS: There was no difference between groups in pain intensity after WALANT and need for intraoperative complementation. There was no significant difference in the amount of opioid applied postoperatively between the groups. There was no difference between groups regarding comfort during surgery. There was no difference in adverse effects and complications between the groups. Hematoma was the most frequent adverse event. No severe adverse events were observed. CONCLUSIONS: The WALANT technique promoted an analgesic effect similar to that of local anesthesia associated with sedation, without increasing adverse effects.


Asunto(s)
Anestesia Local , Síndrome del Túnel Carpiano , Humanos , Anestesia Local/métodos , Mano/cirugía , Estudios Prospectivos , Proyectos Piloto , Síndrome del Túnel Carpiano/cirugía
9.
Eur Rev Med Pharmacol Sci ; 27(20): 9510-9520, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37916318

RESUMEN

OBJECTIVE: Hand osteoarthritis (OA) is associated with considerable disability, especially in the elderly patient population. Paraffin wax (PW) and prolotherapy (P) are non-pharmacological treatment methods used in this setting. This study aimed to compare the therapeutic efficacy of P and PW in hand osteoarthritis. PATIENTS AND METHODS: This study was designed as a single-center, randomized-controlled trial conducted at our Physical Medicine and Rehabilitation Clinic between February 2019 and July 2020. Patients with bilateral hand OA were divided into PW and P treatment groups. The PW group was treated 5 days per week for 2 weeks. The P group received an injection of dextrose solution into the ligaments of painful joints once weekly for three weeks. Visual analog scale (VAS), Duruoz Hand Index (DHI) scale, hand dynamometer for grip strength, and pinch meter for lateral pinch were used for baseline and post-treatment follow-up assessments. RESULTS: Overall, 42 patients were included. The VAS scores significantly decreased in both PW and P groups (p=0.024 and p=0.014). Baseline and third-month post-treatment VAS scores did not significantly differ (p=0.581). The DHI scores improved significantly in both groups (p<0.001 and p<0.001), being higher in the P than in the PW group (p=0.042). Right- and left-hand grip strength increased significantly in PW and P groups (p<0.001, p=0.001; p=0.013, p=0.002, respectively). CONCLUSIONS: Both treatment methods were effective regarding pain and grip strength; however, P improved the hand functions more significantly.


Asunto(s)
Osteoartritis , Proloterapia , Humanos , Anciano , Parafina/uso terapéutico , Fuerza de la Mano , Proloterapia/métodos , Osteoartritis/tratamiento farmacológico , Mano , Resultado del Tratamiento
10.
Cutis ; 112(4): 203-204, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37988297

RESUMEN

Pain and anxiety are common in patients undergoing nail surgery, and injection of local anesthetic is the most uncomfortable part of the procedure. Using a portable massager on the ipsilateral limb during nail injection can reduce pain and decrease patient anxiety. It is a simple and safe way to improve the patient experience during nail surgery.


Asunto(s)
Mano , Dolor , Humanos , Dolor/etiología , Dolor/prevención & control , Anestesia Local/métodos , Anestésicos Locales , Ansiedad/etiología , Ansiedad/prevención & control
11.
Exp Brain Res ; 241(11-12): 2765-2778, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-37855915

RESUMEN

The mental representation of the body in action can be explored using motor imagery (MI) tasks. MI tasks can be allocated along a continuum going from more implicit to more explicit tasks, where the discriminant is the degree of action monitoring required to solve the tasks (which is the awareness of using the mental representation of our own body to monitor our motor imagery). Tasks based on laterality judgments, such as the Hand Laterality Task (HLT) and the Foot Laterality Task (FLT), provide an example of more implicit tasks (i.e., less action monitoring is required). While, an example of a more explicit task is the Mental Motor Chronometry task (MMC) for hands and feet, where individuals are asked to perform or imagine performing movements with their limbs (i.e., more action monitoring is required). In our study, we directly compared hands and feet at all these tasks for the first time, as these body districts have different physical features as well as functions. Fifty-five participants were asked to complete an online version of the HLT and FLT (more implicit measure), and an online version of the MMC task for hands and feet (more explicit measure). The mental representation of hands and feet in action differed only when the degree of action monitoring decreased (HLT ≠ FLT); we observed the presence of biomechanical constraints only for hands. Differently, when the degree of action monitoring increased hands and feet did not show any difference (MMC hands = MMC feet). Our results show the presence of a difference in the mental representation of hands and feet in action that specifically depends on the degree of action monitoring.


Asunto(s)
Mano , Imaginación , Humanos , Imágenes en Psicoterapia/métodos , Movimiento , Pie
12.
Semin Arthritis Rheum ; 63: 152267, 2023 12.
Artículo en Inglés | MEDLINE | ID: mdl-37778090

RESUMEN

INTRODUCTION: Digital ulcers (DUs) are difficult to treat in patients with systemic sclerosis (SSc) and systemic (i.e., pharmacological) therapy is currently considered the 'standard of care'. Our aim was to examine the safety and efficacy of local, non-surgical treatment for SSc-DUs. METHODS: A systematic literature review (SLR) of original research articles up to August, 29 2022 was performed according to the PICO framework. References were independently screened by two reviewers and risk of bias was assed using validated tools. Due to study heterogeneity narrative summaries are used to present data. RESULTS: Among 899 retrieved references, 14 articles were included (2 randomised trials (RTs), and 12 observational (OBS) studies). The most frequently studied procedure (5 studies) was botulin A toxin (hand or single finger) injection with a reported healing rate (HR) of 71%-100%. Amniotic and hydrocolloid membranes were examined in one study each and associated with a good HR. Tadalafil 2% cream was studied in a single study with a reduction in the number of DUs. Vitamin E gel was associated with a reduction in ulcer healing time. Low-level light therapy, hydrodissection and corticosteroid injection, extracorporeal shock wave (ESW) and photobiomodulation were evaluated in a single study each and showed a positive trend. Dimethyl sulfoxide was associated with significant local toxicity. CONCLUSIONS: A range of non-surgical, local treatments for SSc-DUs have been explored and showed efficacy to some extent. We have identified methodological flaws that should be avoided in the design of future studies to explore locally-acting treatments for SSc-DUs.


Asunto(s)
Esclerodermia Sistémica , Úlcera Cutánea , Humanos , Úlcera Cutánea/etiología , Úlcera Cutánea/terapia , Dedos , Mano , Esclerodermia Sistémica/terapia , Esclerodermia Sistémica/tratamiento farmacológico
13.
Zhongguo Zhen Jiu ; 43(9): 990-2, 2023 Sep 12.
Artículo en Chino | MEDLINE | ID: mdl-37697871

RESUMEN

The paper summarizes the academic thought and clinical experience of professor LI De-hua in treatment of facial nerve injury after total parotidectomy with blade needle based on jingjin (muscle region of meridian, sinew/fascia) theory. This disease is located at muscle regions of hand-/foot-three yang meridians; and the sinew/fascia adhesion is its basic pathogenesis, manifested by "transversely-distributed collaterals" and "knotted tendons". In treatment, the knotted tendons are taken as the points. Using the relaxation technique of blade needle, the lesions of sinews/fascia are dissected and removed to release the stimulation or compression to the nerves and vessels so that the normal function of sinews/fascia can be restored.


Asunto(s)
Traumatismos del Nervio Facial , Humanos , Traumatismos del Nervio Facial/etiología , Traumatismos del Nervio Facial/cirugía , Fascia , Pie , Mano , Extremidad Inferior
14.
Zhongguo Zhen Jiu ; 43(9): 1076-80, 2023 Sep 12.
Artículo en Chino | MEDLINE | ID: mdl-37697885

RESUMEN

Renying and Cunkou pulse diagnostic method is one of the important parts of the pulse diagnosis in Huangdi Neijing (Inner Canon of Yellow Emperor) and has been controversial since its proposal. This article takes WANG Shu-he's diagnostic operation as the evidence, and is in reference of the statement, "Cun region (the region ahead of Guan region of Cunkou) determines the human life, that on the left hand refers to Renying, while on the right hand is Qikou". The pulse conditions on the left and right hands represent yin and yang. If Renying pulse on the left is greater, the diseases are in yang meridians, while if Cunkou pulse on the right is bustling, the diseases are in yin meridians. By comparing the pulse condition and strength, as well as the pulse beating (rapid and urgent) between Guan region and region ahead of Guan on the same side, the conditions of three yang and three yin meridians are detected. In treatment, based on the records of Renying and Cunkou pulse diagnosis in Huangdi Neijing, the principles are proposed for reinforcing and reducing methods on hand and foot meridians of yin and yang. Five-shu points and yuan-source points are taken as the main acupoints in acupuncture treatment. During treatment, the changes in pulse conditions should be emphasized specifically and those at Renying and Cunkou regions are the criteria for judging qi arrival and qi regulation.


Asunto(s)
Puntos de Acupuntura , Terapia por Acupuntura , Humanos , Pie , Mano , Frecuencia Cardíaca
15.
Neuroscience ; 530: 56-65, 2023 10 15.
Artículo en Inglés | MEDLINE | ID: mdl-37652289

RESUMEN

Motor imagery based brain-computer interfaces (MI-BCIs) have excellent application prospects in motor enhancement and rehabilitation. However, MI-induced electroencephalogram features applied to MI-BCI usually vary from person to person. This study aimed to investigate whether the motor ability of the individual upper limbs was associated with these features, which helps understand the causes of inter-subject variability. We focused on the behavioral and psychological factors reflecting motor abilities. We first obtained the behavioral scale scores from Edinburgh Handedness Questionnaire, Maximum Grip Strength Test, and Purdue Pegboard Test assessments to evaluate the motor execution ability. We also required the subjects to complete the psychological Movement Imagery Questionnaire-3 estimate, representing MI ability. Then we recorded EEG signals from all twenty-two subjects during MI tasks. Pearson correlation coefficient and stepwise regression were used to analyze the relationships between MI-induced relative event-related desynchronization (rERD) patterns and motor abilities. Both Purdue Pegboard Test and Movement Imagery Questionnaire-3 scores had significant correlations with MI-induced neural oscillation patterns. Notably, the Purdue Pegboard Test of the left hand had the most significant correlation with the alpha rERD. The results of stepwise multiple regression analysis showed that the Purdue Pegboard Test and Movement Imagery Questionnaire-3 could best predict the MI-induced rERD. The results demonstrate that hand dexterity and fine motor coordination are significantly related to MI-induced neural activities. In addition, the method of imagining is also relevant to MI features. Therefore, this study is meaningful for understanding individual differences and the design of user-centered MI-BCI.


Asunto(s)
Interfaces Cerebro-Computador , Electroencefalografía , Humanos , Electroencefalografía/métodos , Imágenes en Psicoterapia/métodos , Mano , Movimiento , Imaginación
16.
J Vis Exp ; (198)2023 08 11.
Artículo en Inglés | MEDLINE | ID: mdl-37590531

RESUMEN

Chronic low back pain (CLBP) is a highly prevalent condition worldwide and a major cause of disability. The majority of patients with CLBP are diagnosed with chronic non-specific low back pain (CNLBP) due to an unknown pathological cause. Manual therapy (MT) is an integral aspect of traditional Chinese medicine and is recognized as Tuina in China. It involves techniques like bone-setting and muscle relaxation manipulation. Despite its clinical efficacy in treating CNLBP, the underlying mechanisms of MT remain unclear. In animal experiments aimed at investigating these mechanisms, one of the main challenges is achieving normative MT on CNLBP model rats. Improving the stability of finger strength is a key issue in MT. To address this technical limitation, a standardized procedure for MT on CNLBP model rats is presented in this study. This procedure significantly enhances the stability of MT with the hands and alleviates common problems associated with immobilizing rats during MT. The findings of this study are of reference value for future experimental investigations of MT.


Asunto(s)
Dolor de la Región Lumbar , Manipulaciones Musculoesqueléticas , Animales , Ratas , Dolor de la Región Lumbar/terapia , China , Dedos , Mano
17.
Eur J Neurosci ; 58(5): 3286-3298, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37501346

RESUMEN

Mental representations of our bodies are thought to influence how we interact with our surroundings. We can examine these mental representations through motor imagery, the imagination of movement using scalp EEG recordings. The visual modality of motor imagery emphasises 'seeing' the imagined movement and is associated with increased activity in the alpha rhythm (8-14 Hz) measured over the occipital regions. The kinaesthetic modality emphasises 'feeling' the movement and is associated with decreased activity in the mu rhythm (8-14 Hz) measured over the sensorimotor cortices. These two modalities can be engaged in isolation or together. We recorded EEG activity while 37 participants (17 left-hand dominant) completed an objective hand motor imagery task. Left-handers exhibited significant activity differences between occipital and motor regions only during imagery of right-hand (non-dominant-hand) movements. This difference was primarily driven by less oscillatory activity in the mu rhythm, which may reflect a shift in imagery strategy wherein participants placed more effort into generating the kinaesthetic sensations of non-dominant-hand imagery. Spatial features of 8-14 Hz activity generated from principal component analysis (PCA) provide further support for a strategy shift. Right-handers also exhibited significant differences between alpha and mu activity during imagery of non-dominant movements. However, this difference was not primarily driven by either rhythm, and no differences were observed in the group's PCA results. Together, these findings indicate that individuals imagine movement differently when it involves their dominant versus non-dominant hand, and left-handers may be more flexible in their motor imagery strategies.


Asunto(s)
Lateralidad Funcional , Corteza Sensoriomotora , Humanos , Movimiento , Electroencefalografía , Imaginación , Mano
18.
J Coll Physicians Surg Pak ; 33(7): 727-731, 2023 07.
Artículo en Inglés | MEDLINE | ID: mdl-37401210

RESUMEN

OBJECTIVE: This study aims to determine the minimal concentration of lidocaine to provide adequate analgesia in wide awake local anaesthesia no tourniquet (WALANT) hand surgeries comparing 3 dilutions of tumescent lidocaine with epinephrine solution. STUDY DESIGN: A randomised control trial. Place and Duration of the Study: The study was held at the Plastic Surgery Department of Mayo Hospital, Lahore, from September 2020 to March 2021. METHODOLOGY: Inclusion criteria were post-traumatic hand contractures and tendon and nerve injuries. The patients were randomised to 3 groups of 30 each: Group A (0.1% lidocaine), Group B (0.2% lidocaine), and Group C (0.3% lidocaine). The dilution of adrenaline also remained constant at 1:200,000. Pain was measured using the Visual Analogue Scale. The three groups were compared for demographics and the total duration of analgesia in minutes. RESULTS: All groups showed adequate pain relief during surgery with no cases requiring conversion to general anaesthesia. The highest total duration of analgesia was seen in the 0.3% group (805.3±195.2 minutes), followed by the 0.2% group (500.4±87.2 minutes) and 0.1% group (381.3±31.6 minutes) (p<0.05). No patient developed any signs of lidocaine toxicity. A low Lidocaine concentration of 0.1% was effective in providing analgesia during surgery though increasing the lidocaine concentration to 0.3% would result in greater post-operative analgesic time without increasing toxicity. CONCLUSION: Adequate analgesia was recorded with all 3 lidocaine concentrations. The greatest pain-free duration was however observed in the  0.3% lidocaine group. KEY WORDS: Wide awake local anaesthesia no tourniquet (WALANT), Lidocaine concentrations, Hand surgery, Analgesia, Adverse effects.


Asunto(s)
Anestesia Local , Lidocaína , Humanos , Anestésicos Locales , Mano/cirugía , Estudios Prospectivos , Epinefrina , Dolor
19.
Surg Radiol Anat ; 45(9): 1083-1087, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37468725

RESUMEN

INTRODUCTION: Hyperhidrosis, causing excessive sweat, can be treated with Botulinum neurotoxin injection. Botulinum toxin, an effective and safe treatment for hyperhidrosis, unfortunately involves significant pain due to multiple injections. This study aims to propose a more efficient and less painful approach to nerve blocks for relief, by identifying optimal injection points to block the median nerve, thereby enhancing palmar hyperhidrosis treatment. METHODS: This study, involving 52 Korean cadaver arms (mean age 73.5 years), measured the location of the median nerve relative to the transverse line at the pisiform level to establish better nerve block injection sites. RESULTS: In between the extensor carpi radialis and palmaris longus, the median nerve was located at an average distance of 47.39 ± 6.43 mm and 29.39 ± 6.43 mm from the transverse line at the pisiform level. DISCUSSION: To minimize discomfort preceding the botulinum neurotoxin injection, we recommend the optimal injection site for local anesthesia to be located 4 cm distal to the transverse line of the pisiform, within the tendons of the palmaris longus and flexor carpi radialis muscles.


Asunto(s)
Toxinas Botulínicas Tipo A , Hiperhidrosis , Humanos , Anciano , Anestesia Local/efectos adversos , Nervio Mediano , Mano , Hiperhidrosis/tratamiento farmacológico , Hiperhidrosis/complicaciones , Dolor/etiología
20.
JBJS Rev ; 11(7)2023 07 01.
Artículo en Inglés | MEDLINE | ID: mdl-37478320

RESUMEN

¼ Wide-awake local anesthesia no tourniquet (WALANT) technique featuring tumescent infiltration of lidocaine with epinephrine at the operative site has broad application in hand surgery including both soft-tissue and bone procedures.¼ The advantages of wide-awake anesthesia include high patient satisfaction, preserved intraoperative finger and wrist motion, cost-effectiveness, improved operating room efficiency, fewer opioids during recovery, and improved access to hand surgery, which may be performed in an office-based setting without the need for anesthesia personnel.¼ In properly selected patients, use of lidocaine with epinephrine in the hand and fingers is safe. Rare postprocedure digital ischemia may be effectively treated with phentolamine rescue.¼ Barriers to adopting wide-awake anesthesia may be overcome by educating resistant stakeholders, including hospital administrators, nurse leaders, and anesthesia colleagues, about the advantages of the WALANT method.¼ The risk of postoperative complications after hand procedures may be mitigated by using the wide-awake technique instead of regional anesthesia with sedation or general anesthesia.


Asunto(s)
Anestesia Local , Procedimientos Ortopédicos , Humanos , Anestesia Local/métodos , Anestésicos Locales , Mano/cirugía , Lidocaína , Epinefrina
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